Publications

  • 2025

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  • 2024

    Screenshot 2024-09-18 at 11

    M Singh, F Roubertie, C Ozturk, P Borchiellini, A Rames, J Bonnemain, SD Gollob, SX Wang, J Naulin, D El Hamrani, N Dugot-Senant, I Gosselin, C Grenet, N L’heureux, ET Roche*, F Kawecki*. “Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models”. Science Translational Medicine, 16, 755, (2024), eadk2936. DOI: 10.1126/scitranslmed.adk2936


  • 2024

    J Deng, J Wu, X Chen, TL Sarrafian, CE Varela, W Whyte, CF Guo, ET Roche, LG Griffiths, H Yuk, CS Nabzdyk, X Zhao. “A bioadhesive pacing lead for atraumatic cardiac monitoring and stimulation in rodent and porcine models”. Science Translational Medicine, 16,752, (2024), eado9003. DOI: 10.1126/scitranslmed.ado9003


  • 2024

    1-s2

    KL Mendez, CE Varela, J Bonnemain, J Deng, H Yuk, B Ayers, W Whyte, X Zhao, ET Roche. “SmartSleeve: A sutureless, soft robotic epicardial device that enables switchable on-off drug delivery in response to epicardial ECG sensing”. Device, (2024), 100419. DOI: 10.1016/j.device.2024.100419


  • 2024

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    L Rosalia, SX Wang, C Ozturk, W Huang, J Bonnemain, R Beatty, GP Duffy, CT Nguyen, ET Roche. “Soft robotic platform for progressive and reversible aortic constriction in a small-animal model”. Science Robotics, 9,91,(2024), eadj9769, 2024. DOI: 10.1126/scirobotics.adj9769


  • 2024

    1-s2

    NA Ward, S Hanley, R Tarpey, LHJ Schreiber. J O’Dwyer, ET Roche, GP Duffy, EB Dolan. “Intermittent actuation attenuates fibrotic behaviour of myofibroblasts”, Acta Biomaterialia, 173, (2024), 80-92. DOI: 10.1016/j.actbio.2023.11.017


  • 2024

    Capture

    Seraina A. Dual, Jennifer Cowger, Ellen Roche, Aditi Nayak. The Future of Durable Mechanical Circulatory Support: Emerging Technological Innovations and Considerations to Enable Evolution of the Field. Journal of Cardiac Failure, Volume 30, Issue 4, 2024, Pages 596-609, ISSN 1071-9164, https://doi.org/10.1016/j.cardfail.2024.01.011.


  • 2024

    ADM

    L. Rosalia, C. Ozturk, S. X. Wang, D. Quevedo-Moreno, M. Y. Saeed, A. Mauskapf, E. T. Roche, Modulating Cardiac Hemodynamics Using Tunable Soft Robotic Sleeves in a Porcine Model of HFpEF Physiology for Device Testing Applications. Adv. Funct. Mater. 2023, 2310085. https://doi.org/10.1002/adfm.202310085


  • 2024

    Dev

    Park C, Singh M, Saeed MY, Nguyen CT, Roche ET. Biorobotic hybrid heart as a benchtop cardiac mitral valve simulator. Device. 2024 Jan 19;2(1):100217. doi: 10.1016/j.device.2023.100217. Epub 2024 Jan 10. PMID: 38312504; PMCID: PMC10836162.


  • 2024

    AM

    M. Singh, D. L. Teodorescu, M. Rowlett, S. X. Wang, M. Balcells, C. Park, B. Bernardo, S. McGarel, C. Reeves, M. R. Mehra, X. Zhao, H. Yuk, E. T. Roche, A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue. Adv. Mater. 2024, 36, 2307288. https://doi.org/10.1002/adma.202307288


  • 2023

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    Luca Rosalia et al. ,Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling.Sci. Robot.8, eade2184(2023).DOI:10.1126/scirobotics.ade2184

    Through the development of a high-fidelity model of aortic stenosis and diastolic dysfunction, this work demonstrates the use of soft robotics to recreate cardiovascular disease, with potential applications in device development, procedural planning, and outcome prediction in industrial and clinical settings.


  • 2023

    Matter

     Verheyen, C.A., Uzel, S.G.M., Kurum, A., Roche, E.T., Lewis, J.A. Integrated data-driven modeling and experimental optimization of granular hydrogel matrices,
    Matter (2023), https://doi.org/10.1016/j.matt.2023.01.011


  • 2023

    Figure_Design

    D. Quevedo-Moreno and E. T. Roche, “Design and Modeling of Fabric-Shelled Pneumatic Bending Soft Actuators,” in IEEE Robotics and Automation Letters, vol. 8, no. 6, pp. 3110-3117, June 2023, doi: 10.1109/LRA.2023.3264734.


  • 2023

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    Samuel Dutra Gollob, Mijaíl Jaén Mendoza, Bon Ho Brandon Koo, Esteban Centeno, Emir A. Vela and Ellen T. Roche. Front. Robot. AI, Sec. Soft Robotics, Volume 10 – 2023 | https://doi.org/10.3389/frobt.2023.1190387


  • 2023

    Screen Shot 2023-06-26 at 11

    Dillon, T.M., Liang, P., Schermerhorn, M.L. , Roche, E.T. A computational program for automated surgical planning of fenestrated endovascular repair. Commun Eng 2, 37 (2023). https://doi.org/10.1038/s44172-023-00083-2


  • 2023

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    Keegan MendezWilliam WhyteBenjamin R. FreedmanYiling FanClaudia E. VarelaManisha SinghJuan C. Cintron-CruzSandra E. RothenbücherJianyu LiDavid J. MooneyEllen T. Roche. Mechanoresponsive Drug Release from a Flexible, Tissue-Adherent, Hybrid Hydrogel Actuator. Advanced Materials. https://doi.org/10.1002/adma.20230330
     


  • 2023

    SR1

    Rachel Beatty et al. ,Soft robot–mediated autonomous adaptation to fibrotic capsule formation for improved drug delivery.Sci. Robot.8,eabq4821(2023).DOI:10.1126/scirobotics.abq4821


  • 2023

    Mag

    Y. Lee, F. Koehler, T. Dillon, G. Loke, Y. Kim, J. Marion, M.-J. Antonini, I. C. Garwood, A. Sahasrabudhe, K. Nagao, X. Zhao, Y. Fink, E. T. Roche, P. Anikeeva, Magnetically Actuated Fiber-Based Soft Robots. Adv. Mater. 2023, 35, 2301916. https://doi.org/10.1002/adma.202301916


  • 2023

    invivo

    F. Flürenbrock et al., “A Soft Robotic Actuator System for in vivo Modeling of Normal Pressure Hydrocephalus,” in IEEE Transactions on Biomedical Engineering, doi: 10.1109/TBME.2023.3325058.


  • 2023

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    M Singh, J Bonnemain, C Ozturk, B Ayers, MY Saeed, D Quevedo-Moreno, M Rowlett, C Park, Y Fan, CT Nguyen, ET Roche.“Robotic right ventricle is a biohybrid platform that simulates right ventricular function in (patho) physiological conditions and intervention”. Nature Cardiovascular Research, 2, (2023), 1310-1326, DOI: 10.1038/s44161-023-00387-8